• Bayer Schering Pharma, 2014-2017
• Else Kröner-Fresenius-Stiftung, 2009-2012
• Grant to Z. Liu, ministry of education, People's Republic of China, 2009-2013
• German Research Foundation Project 2 of the Research Unit FOR 1368 "Hemodynamic Mechanisms of acute Kidney Injury" PA 479/10-1 and 10-2, 2011-2017
• SOMNOmedics
• Promotionsstipendium D. Braun Sonnenfeld-Stiftung, 2017
• German Research Foundation Project A02 of the Collaborative Research Center CRC 1365 "Renoprotection" CRC1365/1, A02;01/2019-12/2022
• German Research Foundation Project A05 of the Collaborative Research Center CRC 1365 "Renoprotection" CRC1365/1, A05;01/2019-12/2022
• German Research Foundation Project A02 of the Collaborative Research Center CRC 1365 "Renoprotection" CRC1365/2, A02;01/2023-12/2023
• German Research Foundation Project C04 of the Collaborative Research Center CRC 1365 "Renoprotection" CRC1365/2, C04;01/2023-12/2023

• Clinic of Urology, PD Dr. J. Busch, Charité
• Group of Prof. J. Jankowski, University Aachen
• Group of Prof. E.Y. Lai, Zhejiang University, Hangzhou
• Group of Prof. R. Liu, University of Mississippi Medical Center, Jackson
• Clinic for Internal Medicine, Dr. H.-H. Minden, Oberhavelkliniken Hennigsdorf
• Group of PD Dr. Rosenberger, Nephrology, Charité
• Group of Prof. R. Schubert, University of Heidelberg
• Group of Prof. Semenyutin, Russian Polenov Neurosurgical Institute, St. Petersburg

Xu Z, Zhang M, Wang W, Zhou S, Yu M, Qiu X, Jiang S, Wang X, Tang C, Li S, Wang CH, Zhu R, Peng WX, Zhao L, Fu X, Patzak A, Persson PB, Zhao L, Mao J, Shu Q, Lai EY, Zhang G: Dihydromyricetin attenuates cisplatin-induced acute kidney injury by reducing oxidative stress, inflammation and ferroptosis. Toxicology and Applied Pharmacology 473:116595, 2023 

Dinh HA, Stölting G, Scholl UI: Cav3.2 (CACNA1H) in primary aldosteronism. Handbook of Exp Pharmacology 279:249-262, 2023 

Fei L, Xu M, Wang H, Zhong C, Jiang S, Lichtenberger FB, Erdoğan C, Wang H, Bonk JS, Lai E, Persson PB, Kovács R, Zheng Z, Patzak A, Khedkar PH: Piezo1 Mediates Vasodilation Induced by Acute Hyperglycemia in Mouse Renal Arteries and Microvessels. Hypertension 104:388-393, 2023

Sholokh A, Walter S, Marko L, McMurray BJ, Sunaga-Franze DY, Xu M, Zuhlke K, Russwurm M, Bartolomaeus TUP, Langanki R, Qadri F, Heuser A, Patzak A, Forslund SK, Bähring S, Borodani T, Persson PB, Maass PG, Bader M, Klussmann E: Mutant PDE3A protects the kidney from hypertension-induced damage. Kidney International 104:90-107, 2023

Sieckmann T, Schley G, Ögel N, Kelterborn S, Boivin F, Fähling M, Ashraf MI, Reichel M, Vigolo E, Hartner A, Lichtenberger F-B, Breiderhoff T, Knauf F, Rosenberger C, Aigner F, Schmidt-Ott K, Scholz H, Kirschner KM: Strikingly conserved gene expression changes of polyamine regulating enzyme among various forms of acute and chronic kidney injury. Kidney International 104:90-107, 2023

Meinert F, Lemâle CL, Major S, Helgers SOA, Dömer P, Mencke R, Bergold MN, Dreier JP, Hecht N, Woitzik J: Less-invasive subdural electrocorticography for investigation of spreading depolarizations in patients with subarachnoid hemorrhage. Front Neurol 13:1091987, 2023 

Horst V, Kola V, Lemale CL, Major S, Winkler MKL, Hecht N, Santos E, Platz J, Sakowitz OW, Vatter H, Dohmen C, Scheel M, Vajkoczy P, Hartings JA, Woitzik J, Martus P, Dreier JP: Spreading depolarization and angiographic spasm are separate mediators of delayed infarcts. Brain Commun. 5:fcad080, 2023

Dauth A, Breborowicz A, Ruan Y, Tang Q, Zadeh JK, Böhm EW, Pfeiffer N, Khedkar PH, Patzak A, Vujacic-Mirski K, Daiber A, Geriecke A: Sulodexide prevents hyperglycemia-induced endothelial dysfunction and oxidative stress in porcine retinal arterioles. Antioxidants 12:388, 2023

Kriuchkova N, Breiderhoff T, Müller D, Yilmaz DE, Demirci H, Drewell H, Günzel D, Himmerkus N, Bleich M, Persson PB, Mutig K: Furosemide rescues hypercalciuria in familial hypomagnesaemia with hypercalciuria and nephrocalcinosis model. Acta Physiol (Oxf). 237:e13927, 2023

Kourpa A, Schulz A, Mangelsen E, Kaiser-Graf D, Koppers N, Stoll M, Rothe M, Bader M, Purfürst B, Kunz S, Gladytz T, Niendorf T, Bachmann S, Mutig K, Bolbrinker J, Panáková D, Kreutz R: Studies in zebrafish and rat models support dual blockade of EP2 and EP4 (prostaglandin E2 receptors type 2 and 4) for renoprotection in glomerular hyperfiltration and albuminuria. Hypertension 80:771-782, 2023 

Zhang D-D, Duan X-P, Mutig K, Rausch F, Xiao Y, Zheng J-Y, Lin D-H, Wang W-H: Calcineurin inhibitors stimulate Kir4.1/Kir5.1 of the distal convoluted tubule to increase NaCl cotransporter. JCI Insight 8:e165987, 2023 

Bothe TL, Bilo G, Parati G, Haberl R, Pilz N, Patzak A: Impact of oscillometric measurement artefacts in ambulatory blood pressure monitoring on estimates of average blood pressure and of its variability: a pilot study. J Hypertens 41:140-149, 2023 

Pilz N, Patzak A, Bothe TL: The pre-ejection period is a highly stress dependent parameter of paramount importance for pulse-wave-velocity based applications. Frontiers in Cardivascular Med 10:1138356, 2023 

Roth B, Bothe TL, Patzak A, Pilz N: Validation of the ABPMpro ambulatory blood pressure monitor in the general population according to AAMI/ESH/ISO Universal Standord (ISO 81060-2:2018). Blood Pressure Monitoring 28:158-162, 2023

Avery EG, Bartolomaeus H, Rauch A, Chen CY, N'Diaye G, Löber U, Bartolomaeus TUP, Fritsche-Guenther R, Rodrigues AF, Yarritu A, Zhong C, Fei L, Tsvetkov D, Todiras M, Park JK, Markó L, Maifeld A, Patzak A, Bader M, Kempa S, Kirwan JA, Forslund SK, Müller DN, Wilck N: Quantifying the impact of gut microbiota on inflammation and hypertensive organ damage. Cardiovasc Res. 119:1441-1452, 2023

Bonk JS, Khedkar PH: Chronic fatigue syndrome: An old public health issue highlighted by the COVID-19 pandemic. Acta Physiol (Oxf). 236:e13863, 2022

Quintanova C, Himmerkus N, Svendsen SL, von Schwerdtner O, Merkel C, Pinckert L, Mutig K, Breiderhoff T, Müller D, Günzel D, Bleich M: Unrecognized role of claudin-10b in basolateral membrane infoldings of the thick ascending limb. Ann N Y Acad Sci. 1517:266-278, 2022 

Pilz N, Patzak A, Bothe TL: Continuous cuffless and non-invasive measurement of arterial blood pressure-concepts and future perspectives. Blood Press 31(1):254-269, 2022 

Wang X, Jiang S, Fei L, Dong F, Xie L, Qiu X, Lei Y, Guo J, Zhong M, Ren X, Yang Y, Zhao L, Zhang G, Wang H, Tang C, Yu L, Liu R, Patzak A, Persson PB, Hultström M, Wei Q, Lai EY, Zheng Z: Tacrolimus Causes Hypertension by Increasing Vascular Contractility via RhoA (Ras Homolog Family Member A)/ROCK (Rho-Associated Protein Kinase) Pathway in Mice. Hypertension 79(10):2228-2238, 2022 

Yilmaz DE, Kirschner K, Demirci H, Himmerkus N, Bachmann S, Mutig K: Immunosuppressive calcineurin inhibitor cyclosporine A induces pro-apoptotic endoplasmic reticulum stress in renal tubular cells. J Biol Chem. 298:101589, 2022

Breiderhoff T, Himmerkus N, Meoli L, Fromm A, Sewerin S, Kriuchkova N, Nagel O, Ladilov Y, Krug S, Quintanova C, Stumpp M, Garbe-Schönberg D, Westernströer U, Merkel C, Brinkhus M, Altmüller J, Schweiger M, Mueller D, Mutig K, Morawski M, Halbritter J, Milatz S, Bleich M, Günzel D: Claudin-10a Deficiency Shifts Proximal Tubular Cl- Permeability to Cation Selectivity via Claudin-2 Redistribution. 
J Am Soc Nephrol. 33:699-717, 2022

Zhou S, Guo J, Liao X, Zhou Q, Qiu X, Jiang S, Xu N, Wang X, Zhao L, Hu W, Xie L, Xie P, Cui Y, Yang Y, Patzak A, Persson PB, Mao J, Lai EY: rhADAMTS13 reduces oxidative stress by cleaving VWF in ischemia/reperfusion induced acute kidney injury. Acta Physiologica :e13778, 2022

Dong F, Jiang S, Tang C, Wang X, Ren X, Wei Q, Tian J, Hu W, Guo J, Fu X, Liu L, Patzak A, Persson PB, Gao F, Lai EY, Zhao L: Trimethylamine N-oxide promotes hyperoxaluria-induced calcium oxalate deposition and kidney injury by activating autophagy. Free Radical Biology and Medicine 179:288-300, 2022 

Bothe TL, Dippel LJ, Pilz N: The art of planning – How many samples are enough? Acta Physiologica 23:e13746, 2022 

Jiang S, Shui Y, Cui Y, Tang C, Wang X, Qiu X, Hu W, Fei L, Li Y, Zhang S, Zhao L, Xu N, Dong F, Ren X, Liu R, Persson PB, Patzak A, Lai EY, Wei Q, Zheng Z: Gut microbiota dependent trimethylamine N-oxide aggravates angiotensin II-induced hypertension. Redox Biology 46: 102115, 2021

Hu J, Xu Y, Bachmann S, Mutig K: Angiotensin II receptor blockade alleviates calcineurin inhibitor nephrotoxicity by restoring cyclooxygenase 2 expression in kidney cortex. Acta Physiologica 232:e13612, 2021

Birk M, Baum E, Zadeh JK, Manicam C, Pfeiffer N, Patzak A, Helmstädter J, Steven S, Kuntic M, Daiber A, Gericke A: Angiotensin II induces oxidative stress and endothelial dysfunction in mouse ophthalmic arteries via involvement of AT1 receptors and NOX2. Antioxidants 10:1238, 2021

Cordes S, Mokhtari Z, Bartosova M, Mertlitz S, Riesner K, Shi Y, Mengwasser J, Kalupa M, McGeary A, Schleifenbaum J, Schrezenmeier J, Bullinger L, Diaz-Ricart M, Palomo M, Carreras E, Beutel G, Schmitt CP, Beilhack A, Penack O: Endothelial damage and dysfunction in acute graft-versus-host disease. Haematologica 106(8):2147-2160, 2021

Bothe TL, Patzak A, Schubert R, Pilz N: Getting it right matters! Covid-19 pandemic analogies to everyday life in medical sciences. Acta Physiologica 233:e13714, 2021

Zhong C, Xu M, Boral S, Summer H, Lichtenberger FB, Erdogan C, Gollasch M, Golz S, Persson PB, Schleifenbaum J, Patzak A, Khedkar PH: Age impairs soluble guanylyl cyclase function in mouse mesenteric arteries. Int J Molecular Sciences 22:11412, 2021

Indorf P, Patzak A, Lichtenberger FB: Drug metabolism in animal models and humans: Translational aspects and chances for individual therapy. Acta Physiologica 233:e13734, 2021

Ivanets NN, Svistunov AA, Chubarev VN, Kinkulkina MA, Tikhonova YG, Syzrantsev NS, Sologova SS, Ignatyeva NV, Mutig K, Tarasov VV: Can molecular biology propose reliable biomarkers for diagnosing major depression? Current Pharmaceutical Design 27(2):305-318, 2021

Patzak A: Measuring blood pressure by a cuffless device using the pulse transit time. Int. J Cardiol. & Hyperten 8, 2021

Zhang YY, Xu CX, Ye Q, Tong LX, Jiang H, Zhu XJ, Huang LM, Lin WQ, Fu HD, Wang JJ, Persson PB, Lai EY, Mao JH: Podocyte apoptosis in diabetic nephropathy by BASP1 activation of the p53 pathway via WT1. Acta Physiologica 232:e13634, 2021

Lichtenberger FB, Patzak A: AKI and CKD. Acta Physiologica 232:e13646, 2021

Hu WP, Jiang S, Liao YX, Li JH, Dong F, Guo J, Wang XH, Fei LY, Cui Yu, Ren XQ, Xu N, Zhao L, Chen LM, Zheng Y, Li LL, Patzak A, Persson PB, Zheng ZH, Lai EY: High phosphate impairs arterial endothelial function through AMPK-related pathways in mouse resistance arteries. Acta Physiologica 231:e13595, 2021

Ruan Y, Patzak A, Pfeiffer N, Gericke A: Muscarinic acetylcholine receptors in the retina-Therapeutic implications. Int J of Molecular Sciences 22:4989, 2021

Bothe TL, Patzak A: Significant significance? Acta Physiologica :e13665, 2021

Stehle D, Xu MZ, Schomber T, Hahn MG, Schweda F, Feil S, Kraehling JR, Patzak A, Sandner P, Feil R, Bénardeau A: Novel sGC activators increase glomerular cGMP, induce vasodilation, and improve blood flow in the murine kidney. Br J Pharmacology : 2021, epub ahead of print

Semenyutin, V, Aliev V, Panuntsev G, Patzak A: Perioperative dynamics of intracranial B-waves of blood flow velocity in the basal cerebral arteries in patients with brain arteriovenous malformation. Acta Neurochir Suppl. 131:63-68, 2021

Zhou S, Guo J, Zhao L, Liao Y, Zhou Q, Yu C, Hu W, Chen J, Ren X, Wei Q, Jiang S, Zheng Y, Li L, Wilcox CS, Persson PB, Patzak A, Tian J, Lai EY: ADAMTS13 inhibits oxidative stress and ameliorates progressive chronic kidney disease following ischaemia/reperfusion injury. Acta Physiologica 231:e13586, 2021

Wennysia IC, Zhao L, Schomber T, Braun D, Golz S, Summer H, Benardeau A, Lai EY, Lichtenberger F-B, Schubert R, Persson PB, Xu MZ, Patzak A: Role of soluble guanylyl cyclase in renal afferent and efferent arterioles. American Journal of Physiology, Renal Physiology 320:F193-F202, 2021

Ye Q, Lai EY, Luft FC, Persson PB, Mao JH: SARS-CoV-2 effects on the renin-angiotensin-aldosterone system, therapeutic implications.       
Acta Physiologica 231:e13608, 2021

Zhao L, Cao X, Li L, Wang X, Wang Q, Jiang S, Tang C, Zhou S, Xu N, Cui Y, Hu W, Fei L, Zheng Z, Chen L, Schmidt MO, Wei Q, Zhao J, Labes R, Patzak A, Wilcox CS, Fu X, Wellstein A, Lai EY: Acute kidney injury sensitizes the brain vasculature to AngII (Angiotensin II) constriction via FGFBP1 (Fibroblast Growth Factor Binding Protein 1). Hypertension 76:1924-1934, 2020 

Khedkar Pratik H: Intermittent fasting – The new lifestyle? Acta Physiologica 229: e13518, 2020 

Cordes S, Mokhtari Z, Bartosova M, Mertlitz S, Riesner K, Shi Y, Mengwasser J, Kalupa M, McGeary A, Schleifenbaum J, Schrezenmeier J, Bullinger L, Diaz-Ricart M, Palomo M, Carreras E, Beutel G, Schmitt CP, Beilhack A, Penack O: Endothelial damage and dysfunction in acute graft-versus-host disease. Haematologica : e-pub ahead of print, 2020 

Erdogan C: Improvement of physical training by performance enhancing substances. Acta Physiologica 230:e13517, 2020

Aichinger G, Lichtenberger FB, Steinhauer TN, Flörkemeier I, Del Favero G, Clement B, Marko D: The Aza-Analogous Benzo[c]phenanthridine P8-D6 acts as a dual topoisomerase I and II poison, thus exhibiting potent genotoxic properties. Molecules 25: 1524, 2020

Khedkar PH, Patzak A: SARS-CoV-2: What do we know so far? Acta Physiologica 229:e13470, 2020

Xu N, Jiang S, Persson PB, Persson EA, Lai EY, Patzak A: Reactive oxygen species in renal vascular function. Acta Physiologica :e13477, 2020

Schleifenbaum J: Alamandine and its receptor MrgD pair up to join the protective arm of the renin-angiotensin system. Front Med (Lausanne) 6: 107 10.3389/fmed.2019.00107, 2019

Zhong C, Schleifenbaum J: Genetically encoded calcium indicators: a new tool in renal hypertension research. Front Med (Lausanne) 6: 128 10.3389/fmed.2019.00128, 2019

Zadeh JK, Garcia-Bardon A, Hartmann EK, Pfeiffer N, Omran W, Ludwig M, Patzak A, Xia N, Li H, Gericke A: Short-time ocular ischemia induces vascular endothelial dysfunction and ganglion cell loss in the pig retina. Int J Mol Sci 20: pii: E4685, 2019

Berndt N, Patzak A, Holzhütter HG: Metabolic modeling of kidney diseases: lessons learned from the liver. Acta Physiologica 227:e13350, 2019

Kaßmann M, Szijarto IA, Garcia-Prieto CF, Fan G, Schleifenbaum J, Anistan YM, Tabeling C, Shi Y, le Noble F, Witzenrath M, Huang Y, Marko L, Nelsen MT, Gollasch M: Role of ryanodine type 2 receptors in elementary Ca2+ signaling in arteries and vascular adaptive responses. Journal of the American Heart Association 8:e010090, 2019

Zadeh JK, Ruemmler R, Hartmann EK, Ziebart A, Ludwig M, Patzak A, Xia N, Li H, Pfeiffer N, Gericke A: Responses of retinal arterioles and ciliary arteries in pigs with acute respiratory distress syndrome (ARDS). Exp Eye Res. 184:152-161, 2019

Pramsohler S, Schilz R, Patzak A, Rausch L, Netzer NC: Periodic breathing in healthy young adults in normobaric hypoxia equivalent to 3500 m, 4500 m, and 5500 m altitude. Sleep Breath 23:703-709, 2019

Patzak A, Ludwig M: Models. Acta Physiol (Oxf). 225:e13237, 2019

Zhou S, Jiang S, Guo J, Xu N, Wang Q, Zhang G, Zhao L, Zhou Q, Fu X, Li L, Patzak A, Hultström M, Lai EY: ADAMTS13 protects mice against renal ischemia-reperfusion injury by reducing inflammation and improving endothelial function. Am J Physiol Renal Physiol. 316:F134-F145, 2019

Shan J, Wang X, Wie J, Zhang G, Zhang J, Peng X, Xu L, Wang L, Zhao L, Li L, Wilcox CS, Chen J, Lai EY, Liu R: NaHCO3 dilates mouse afferent arteriole via Na+/HCO3- cotransporters NBCs. Hypertension 74:1104-1112, 2019

Xu N, Wang Q, Jiang S, Wang Q, Hu W, Zhou S, Zhao L, Xie L, Chen J, Wellstein A, Lai EY: Fenofibrate improves vascular endothelial function and contractility in diabetic mice. Redox Biology 20:87-97, 2019

Witte J, Mühlbauer M, Braun D, Steinbach A, Golchert J, Rettig R, Grisk O: Renal soluble guanylate cyclase is downregulated in sunitinib-induced hypertension. Journal of the American Heart Association 7:e009557, 2018

Klopsch C, Skorska A, Ludwig M, Lemcke H, Maass G, Gaebel R, Beyer M, Lux C, Toelk A, Müller K, Maschmeier C, Rohde S, Mela P, Müller-Hilke B, Jockenhoevel S, Vollmar B, Jaster R, David R, Steinhoff G:
Intramyocardial angiogenetic stem cells and epicardial erythropoietin save the acute ischemic heart
Disease Models & Mechanisms 11: dmm033282, 2018

Braun D, Zollbrecht C, Dietze S, Schubert R, Golz S, Summer H, Persson PB, Carlström M, Ludwig M, Patzak A: Hypoxia/Reoxygenation of rat renal arteries impairs vasorelaxation via modulation of endothelium-independent sGC/cGMP/PKG signaling. Front Physiol 9: 480, 2018

Zhang S, Huang Q, Wang Q, Wang Q, Cao X, Zhao L, Xu N, Zhuge Z, Mao J, Fu X, Liu R, Wilcox CS, Patzak A, Li L, Lai EY: Enhanced renal afferent arteriolar reactive oxygen species and contractility to endothelin-1 are associated with canonical Wnt signaling in diabetic mice. Kidney Blood Press Res 43: 860-871, 2018

Willière Y, Borschewski A, Patzak A, Nikitina T, Dittmayer C, Daigeler AL, Schuelke M, Bachmann S, Mutig K: Caveolin 1 promotes renal water and salt reabsorption. Scientific Reports 8: 545, 2018

Högner A, Krause H, Jandrig B, Kasim M, Fuller TF, Schostak M, Erbersdobler A, Patzak A, Kilic E: PBRM1 and VHL expression correlate in human clear cell renal cell carcinoma with differential association with patient's overall survival. Urol Oncol. 36: 94.e1-94.e14, 2018

Pahlitzsch TM, Liu ZZ, Al-Masri A, Braun D, Dietze S, Persson PB, Schunck WH, Blum M, Kupsch E, Ludwig M, Patzak A: Hypoxia-reoxygenation enhances murine afferent arteriolar vasoconstriction by angiotensin II. Am J Physiol Renal Physiol. 314: F430-F438, 2018

Gehring J, Gesche H, Drewniok G, Küchler G, Patzak A: Nocturnal blood pressure fluctuations measured by using pulse transit time in patients with severe obstructive sleep apnea syndrome. Sleep Breath. 22: 337-343, 2018

Gao X, Liu ZZ, Mohammed H, Braun D, Zhuge Z, Liu M, Lai EY, Jansson L, Carlström M, Patzak A, Persson AEG: Extravasal albumin concentration modulates contractile responses of renal afferent arterioles. Acta Physiol. 222:e12925, 2018

Semenyutin VB, Asaturyan GA, Nikiforova AA, Aliev VA, Panuntsev GK, Iblyaminov VB, Savello AV, Patzak A: Predictive Value of Dynamic Cerebral Autoregulation Assessment in Surgical Management of Patients with High-Grade Carotid Artery Stenosis. Front Physiol. 8: 872, 2017. doi: 10.3389/fphys.2017.00872. eCollection 2017

Klopsch C, Skorska A, Ludwig M, Gaebel R, Lemcke H, Kleiner G, Beyer M, Vollmar B, David R, Steinhoff G: Cardiac Mesenchymal Stem Cells Proliferate Early in the Ischemic Heart. Eur Surg Res. 58(5-6): 341-353, 2017

Braun D, Dietze S, Pahlitzsch TMJ, Wennysia IC, Persson PB, Ludwig M, Patzak A: Short-term hypoxia and vasa recta function in kidney slices. Clin Hemorheol Microcirc. 67: 475-484, 2017

Liu ZZ, Mathia S, Pahlitzsch T, Wennysia IC, Persson PB, Lai EY, Högner A, Xu MZ, Schubert R, Rosenberger C, Patzak A: Myoglobin facilitates angiotensin II-induced constriction of renal afferent arterioles. Am J Physiol Renal Physiol. 312: F908-F916, 2017

Fähling M, Seeliger E, Patzak A, Persson PB: Understanding and preventing contrast-induced acute kidney injury. Nat Rev Nephrol 13: 169-180, 2017. Review

Ludwig M, Högner A, Patzak A: You are not alone. Acta Physiol (Oxf) 219: 337-338, 2017

Tsvetkov D, Kaßmann M, Tano JY, Chen L, Schleifenbaum J, Voelkl J, Lang F, Huang Y, Gollasch M: Do KV 7.1 channels contribute to control of arterial vascular tone? Br J Pharmacol. 174(2): 150-162, 2017

Zhao L, Gao Y, Cao X, Gao D, Zhou S, Zhang S, Cai X, Han F, Wilcox CS, Li L, Lai EY: High-salt diet induces outward remodeling of efferent arterioles in mice with reduced renal mass. Acta Physiologica 219:654-661, 2017

Huang Q, Wang Q, Zhang S, Jiang S, Zhao L, Yu L, Hultström M, Patzak A, Li L, Wilcox CS, Lai EY: Increased hydrogen peroxide impairs angiotensin II contractions of afferent arterioles in mice after renal ischaemia-reperfusion injury. Acta Physiologica 218: 136-145, 2016

Zhang G, Wang Q, Zhou Q, Wang R, Xu M, Wang H, Wang L, Wilcox CS, Liu R, Lai EY: Protective effect of tempol on acute kidney injury through PI3K/Akt/Nrf2 signaling pathway. Kidney Blood Pressure Res. 41: 129-138, 2016

Dietze S, Patzak A: Biomarkers. Acta Physiologica 216: 379-382, 2016

Vandekerckhove L, Vermeulen Z, Liu ZZ, Boimvaser S, Patzak A, Segers VF, De Keulenaer GW: Neuregulin-1 attenuates development of nephropathy in a type 1 diabetes mouse model with high cardiovascular risk. Am J Physiol Endocrinol Metab. 310: E495-E504, 2016 

Skorska A, Haehling von S, Ludwig M, Lux CA, Gaebel R, Kleiner G, Klopsch Ch, Dong J, Curato C, Altarche-Xifró W, Slavic S, Unger T, Steinhoff G, Li J, David R: The CDA4+AT2R+T cell subpopulation improves post-infarctions remodelling and restores cardiac function. J Cellular Molecular Med. 19: 1975-1985, 2015

Ludwig M, Tölk A, Skorska A, Maschmeier Ch, Gaebel R, Lux CA, Steinhoff G, David R: Exploiting AT2R to improve CD177 stem cell function in vitro and in vivo - perspective for cardiac stem cell therapy. Cellular Physiol and Biochem. 37: 77-93, 2015

Ludwig M, Högner A: High expectations: from treatment to prevention. Acta Physiologica 215: 2-4, 2015

Patzak A, Mendoza Y, Gesche H, Konermann M: Continuous blood pressure measurement using the pulse transit time: comparison to intra-arterial measurement. Blood Pressure 24: 217-221, 2015

Nikitina T, Zavaritskaya O, Semenyutin V, Persson PB, Patzak A, Sendeski M: Effects of iodinated contrast media in a novel model for cerebral vasospasm. Arq Neuropsiquitr 73: 125-131, 2015

Patzak A: Kontinuierliche nicht-invasive Blutdruckmessung mittels Pulswellenlaufzeit. Klinikarzt 44: 238-242, 2015 

Kaufmann J, Martinka P, Moede O, Sendeski M, Steege A, Fähling M, Hultström M, Gaestel M, Moraes-Silva IC, Nikitina T, Liu ZZ, Zavaritskaya O, Patzak A: Noradrenaline enhances angiotensin II responses via p38 MAPK activation after hypoxia/re-oxygenation in renal interlobar arteries. Acta Physiol (Oxf). 213: 920-932, 2015 

Patzak A, Carlström M, Sendeski MM, Lai EY, Liu ZZ, Sällström J, Flöge J, Heintz B, Jankowski J, Jankowski V: Diadenosine pentaphosphate modulates glomerular arteriolar tone and glomerular filtration rate. Acta Physiol (Oxf) 213: 285-93, 2015

Gao X, Peleli M, Zollbrecht C, Patzak A, Persson AE, Carlström M: Adenosine A1 receptor-dependent and independent pathways in modulating renal vascular responses to angiotensin II. Acta Physiol (Oxf) 213: 268-76, 2015

Chen L, Kaßmann M, Sendeski M, Tsvetkov D, Marko L, Michalick L, Riehle M, Liedtke WB, Kuebler WM, Harteneck C, Tepel M, Patzak A, Gollasch M: Functional transient receptor potential vanilloid 1 and transient receptor potential vanilloid 4 channels along different segments of the renal vasculature. Acta Physiol (Oxf) 213: 481-91, 2015

Laspas P, Goloborodko E, Sniatecki JJ, Kordasz ML, Manicam C, Wojnowski L, Li H, Patzak A, Pfeiffer N, Gericke A: Role of nitric oxide synthase isoforms for ophthalmic artery reactivity in mice. Exp Eye Res 127: 1-8, 2014

Bäumler H, Xiong Y, Liu ZZ, Patzak A, Georgieva R: Novel hemoglobin particles--promising new-generation hemoglobin-based oxygen carriers. Artif Organs 38(8): 708-14, 2014

Brinkmann O, Schmerbach K, Tietge U, Dietrich T, Guski H, Linz D, Kühn H, Patzak A, Wilfert K: Changes in arterial function in a mouse model of human familial hypercholesterolemia. Acta Physiologica 211: 61-72, 2014

Reuter S, Patzak A, Mrowka R: Hypertension. Acta Physiologica 211: 1-4, 2014

Potthoff SA, Fähling M, Clasen T, Mende S, Ishak B, Suvorava T, Stamer S, Thieme M, Sivritas SH, Kojda G, Patzak A, Rump LC, Stegbauer J: Angiotensin-(1-7) modulates renal vascular resistance through inhibition of p38 mitogen-activated protein kinase in apolipoprotein E-deficient mice. Hypertension 63: 265-272, 2014

Muoio V, Persson PB, Sendeski MM: The neurovascular unit – concept review. Acta Physiologica 210: 790-798, 2014

Schmerbach K, Patzak A: The metabolic syndrome: is it the mother's fault? Acta Physiologica 210: 702-704, 2014

Liu Z, Schmerbach K, Lu Y, Perlewitz A, Nikitina T, Cantow K, Seeliger E, Persson PB, Patzak A, Liu R, Sendeski M: Iodinated contrast media cause direct tubular cell damage, leading to oxidative stress, low nitric oxide, and impairment of tubulo-glomerular feedback. American Journal of Physiology, Renal Physiology 306: F864-F872, 2014

Schmerbach K, Patzak A: Pathophysiological mechanisms in acute mountain sickness. Acta Physiologica 209: 246-249, 2013

Xiong Y, Liu ZZ, Georgieva R, Smuda K, Steffen A, Sendeski M, Voigt A, Patzak A, Bäumler H: Nonvasoconstrictive haemoglobin particles as oxygen carriers. ACS NANO 7: 7454-7461, 2013 

Liu N, Patzak A, Zhang J: CXCR4-overexpressing bone marrow-derived mesenchymal stem cells improve repair of acute kidney injury. Am J Physiol Renal Physiol 305: F1064-F1073, 2013

Persson AEG, Lai EY, Gao X, Carlström M, Patzak A: Interactions between adenosine, angiotensin II and nitric oxide on the afferent arteriole influence sensitivity of the tubuloglomerular feedback. Frontiers in Physiology 4(187):1-4, 2013

Henning A, Patzak A: Continuous blood pressure messurement using pulse transit time. Somnologie 17(2):p.104-110, 2013

Sendeski MM, Liu ZZ, Perlewitz A, Busch JF, Ikromov O, Weikert S, Persson PB, Patzak A: Functional characterization of isolated, perfused outer medullary descending human vasa recta. Acta Physiologica 208:50-56, 2013

Liu N, Patzak A, Sendeski MM: Nitric oxide and reactive oxygen species in renal medulla pathophysiology - so small yet so special: the renal medulla. Acta Physiologica 208:144-147, 2013 

Sendeski MM, Bondke Persson A, Liu ZZ, Busch JF, Weikert S, Persson PB, Hippenstiel S, Patzak A: Iodinated contrast media cause endothelial damage leading to vasoconstriction of human and rat vasa recta. Am J Physiol Renal Physiol. 303: F1592-F1598, 2012

Schrezenmeier E, Zollmann FS, Seidel K, Böhm C, Schmerbach K, Kroh M, Kirsch S, Klare S, Bernhard S, Kappert K, Goldin-Lang P, Skuballa W, Unger T, Funke-Kaiser H: Moderate Correlations of in vitro versus in vivo Pharmacokinetics Questioning the Need of Early Microsomal Stability Testing. Pharmacology 90: 307-315, 2012

Schmerbach K, Kalk P, Wengenmayer C, Lucht K, Unger T, Hocher B, Thoene-Reineke C: Renal outcome in equipotent antihypertensive treatment with telmisartan, ramipril and in combination in SHR-SP rats. Clin Lab. 58: 625-633, 2012

Liu ZZ, Viegas VU, Perlewitz A, Lai EY, Persson PB, Patzak A, Sendeski MM: Iodinated contrast media differentially affect afferent and efferent arteriolar tone and reactivity in mice: A possible explanation for reduced glomerular filtration rate. Radiology 265: 762-771, 2012

Fähling M, Bondke Persson A, Klinger B, Benko E, Steege A, Kasim M, Patzak A, Persson PB, Wolf G, Blüthgen N, Mrowka R: Multilevel regulation of HIF-1 signaling by TTP. Mol Biol Cell 23: 4129-4141, 2012

Li Y, Seidel K, Marschall P, Klein M, Hope A, Schacherl J, Schmitz J, Menk M, Schefe JH, Reinemund J, Hugel R, Walden P, Schlosser A, Volkmer R, Schimkus J, Kölsch H, Maier W, Kornhuber J, Fröhlich L, Klare S, Kirsch S, Schmerbach K, Scheele S, Grittner U, Zollman F, Goldin-Lang P, Peters O, Kintscher U, Unger T, Funke-Kaiser H: A polymorphic microsatellite repeat within the ECE-1c promoter is involved in transcriptional start site determination, human evoluation, and alzheimer's disease. The J Neuroscience 32: 16807-16820, 2012

Hennig A, Gesche H, Fietze I, Penzel T, Glos M, Patzak A: Messung von apnoebezogenen Blutdruckänderungen mittels Pulstransitzeit und Penaz-Prinzip. Atemwegs- und Lungenkrankheiten 38: 1-8, 2012

Semenyutin V, Aliev V, Bersnev V, Patzak A, Rozhchenko L, Kozlov A, Ramazanov S: Informativity of pulsatility index and cerebral autoregulation in hydrocephalus. Perspectives in Medicine 1: 311-315, 2012

Viegas VU, Liu ZZ, Nikitina T, Perlewitz A, Zavaritskaya O, Schlichting J, Persson PB, Regitz-Zagrosek V, Patzak A, Sendeski MM: Angiotensin II type 2 receptor mediates sex differences in mice renal interlobar arteries response to angiotensin II. J Hyperten 30: 1791-1798, 2012

Schmerbach K, Patzak A: The renin-angiotensin system - a functional 'jack-of-all-trades'. Acta Physiol. (Oxford) 205: 453-455, 2012

Perlewitz A, Persson AE, Patzak A: The juxtaglomerular apparatus. Acta Physiol. (Oxford) 205: 6-8, 2012

Seeliger E, Sendeski M, Rihal CS, Persson PB: Contrast-induced kidney injury: mechanisms, risk factors, and prevention. European Heart Journal 33: 2007-2015, 2012

Gesche H, Grosskurth D, Küchler G, Patzak A: Continuous blood pressure measurement by using the pulse transit time: comparison to a cuff-based method. Eur J Appl Physiol. 112: 309-315, 2012

Seidel K, Kirsch S, Lucht K, Zaade D, Reinemund J, Schmitz J, Klare S, Li Y, Schefe JH, Schmerbach K, Goldin-Lang P, Zollmann FS, Thöne-Reineke C, Unger T, Funke-Kaiser H: The Promyelocytic Leukemia Zinc Finger (PLZF) Protein Exerts Neuroprotective Effects in Neuronal Cells and is Dysregulated in Experimental Stroke. Brain Pathology 21: 31-43, 2011

Thoene-Reineke C, Rumschüssel K, Schmerbach K, Krikov M, Wengenmayer C, Godes M, Mueller S, Villringer A, Steckeling U, Namsolleck P, Unger T: Prevention and Intervention Studies with Telmisartan, Ramipril and Their Combination in Different Rat Stroke Models. PLoS One 6(8): e23646, 2011

Goa X, Patzak A, Sendeski M, Scheffer PG, Teerlink T, Sallstrom J, Fredholm BB, Persson AE, Carlstrom M: Adenosine A1 receptor deficiency diminishes afferent arteriolar and blood pressure responses during nitric oxide inhibition and angiotensin II treatment. Am J Physiol Regu, Integr and Comp Physiol. 301: R1669-R1681, 2011

Gericke A, Sniatecki JJ, Goloborodko E, Steege A, Zavaritskaya O, Vetter JM, Grus FH, Patzak A, Wess K. Pfeiffer N: Identification of the muscarinic acetylcholine receptor subtype mediating cholinergic vasodilation in murine retinal arterioles. Invest Ophthalmol Vis Sci. 52: 7479-7484, 2011

Gericke A, Kordasz ML, Steege A, Sanbe A, Goloborodko E, Vetter JM, Patzak A, Pfeiffer N: Functional role of α 1-adrenoceptor subtypes in murine ophthalmic arteries. Invest Ophthalmol Vis Sci. 52:4795-4799, 2011

Sendeski MM: The pathophysiology of renal tissue damage by iodinated contrast media. Clin Exp Pharmacol Physiol. (CEEP) 38: 292-299, 2011 

Gericke A, Sniatecki JJ, Mayer VG, Goloborodko E, Patzak A, Wess J, Pfeiffer N: Role of M1, M3 and M5 muscarinic acetylcholine receptors in cholinergic dilation of small arteries studied with gene-targeted mice. Am J Physiol Heart Circ Physiol. 300: H1602-H1608, 2011 

Schildroth J, Rettig-Zimmermann J, Kalk P, Steege A, Fähling M, Sendeski M, Paliege A, Lai EY, Bachmann S, Persson PB, Hocher B, Patzak A: Endothelin type A and B receptors in the control of afferent and efferent arterioles in mice. Nephrol. Dialysis Transplant. 26: 779-789, 2011

Sendeski M, Patzak A, Persson PB: Constriction of the vasa recta, the vessels supplying the area at risk for acute kidney injury, by four different iodionated contrast media, evaluating ionic, non-ionic, monomeric and dimeric agents. Invest. Radiology 45: 453-457, 2010

Carlström M, Lai EY, Ma Z, Steege A, Patzak A, Eriksson UJ, Lundberg JO, Wilcox CS, Persson AEG: Superoxide dismutase 1 limits renal microvascular remodeling and attenuates arteriole and blood pressure responses to angiotensin II via modulation of nitric oxide bioavailability. Hypertension 56: 907-913, 2010

Cao C, Edwards A, Sendeski M, Lee-kwon W, Cui L, Cai CY, Patzak A, Pallone TL: Intrinsic nitric oxide and superoxide production regulates descending vasa recta contraction. Am J Physiol - Renal Physiol 299: F1056-F1064, 2010